Neuropathic leg pain can be treated by the following methods: First, if it is neuropathic pain in the lower limbs caused by lumbar disc herniation and lumbar spinal stenosis, conservative treatment, such as ultrashort wave therapy, microwave therapy, lumbar traction therapy and bed rest, can improve the clinical symptoms of neuropathic leg pain through comprehensive treatment. If it is more serious, surgical treatment should be considered to remove the herniated disc, enlarge the narrow spinal canal and release the nerve compression, which can completely relieve the neuropathic leg pain. Secondly, if it is neuropathic leg pain caused by pear-shaped muscle syndrome, massage treatment should be given to the pear-shaped muscle to make it relax, and with ultrashort wave therapy and oral administration of celecoxib and loxoprofen sodium. It can reduce the inflammation, restore the nerve conduction function and relieve the symptoms of neuropathic pain in the lower limbs. Early diagnosis and early treatment are beneficial to the rapid relief of symptoms, while patients should usually pay attention to the protection of the lumbar spine and the pear-shaped muscle.