Acne refers to acne, a chronic inflammatory skin disease of the sebaceous gland units of hair follicles that can affect people of all ages, with a high incidence in adolescents. The treatments for acne in middle school include general treatment, medication, and physical therapy. 1. General treatment: for general treatment, choose water or suitable cleansing products to remove excess oil, flakes and bacterial mixtures on the skin surface, pay attention to oil control and moisturizing, and use mild moisturizing milk externally. Avoid squeezing and scratching the skin lesions with hands. Limit the intake of high glycemic index foods and milk that may trigger or aggravate acne, keep bowel movement smooth, and avoid staying up all night. 2. Medication: Common topical medications include isotretinoin cream, adapalene gel, fusidic acid cream, benzoyl peroxide gel, etc. Systemic medications include antibiotics such as doxycycline hydrochloride tablets. 3. Physical therapy: Physical therapy includes photodynamic therapy and laser therapy; photodynamic therapy can destroy the reaction of Propionibacterium acnes and laser therapy can repair scars and acne marks left by acne. Parents are advised to bring acne to the hospital when it develops in middle school and receive targeted treatment from the doctor. Medications should be used according to the doctor’s instructions, and should not be self-medicated.