Swelling pain in the eyes and temples may be related to certain diseases, or it may be caused by medications, environmental factors, lifestyle and so on. 1. Diseases: Paroxysmal migraine, cluster headache, intracranial tumors and other diseases can cause patients to experience swelling and pain in the eyes and temples. 2. Drugs: overdose of drugs can cause drug overdose headache, such as overdose of Triptans, opiate painkillers. 3. Environmental factors: cold and other causes can cause eye and temple swelling and pain. 4. Lifestyle: Tension, overwork, insomnia and other factors can also cause eye and temple swelling and pain. There are many causes of eye and temple swelling and pain. For serious cases, it is recommended to go to the hospital in time to find out the cause and follow the doctor’s instructions for treatment.