Craniosynostosis is a relatively common craniosynostosis in neurosurgery, and the age of onset of this disorder is relatively discrete. Many children may suffer from cranial defects due to car accidents, falls from height, craniotomy for craniosynostosis, and so on. Cranial defects can have many adverse effects on the human body, so they need to be repaired in a timely manner. Among the materials currently used in clinical practice, polyetheretherketone (PEEK) is a new type of polymer material with excellent performance and is becoming a new trend in cranial repair materials. PEEK material as a new material with excellent performance, is not affected by the development of children. Polyetheretherketone PEEK is a very advanced cranial repair material that fully complies with national standards for human implants, and its properties are basically comparable to those of autologous cranial bone, with excellent histocompatibility and no impact on the growth and development of children. Our team not only adopts this advanced PEEK material, but also constantly carries out optimization design and technical innovation of the material, and also introduces the concept of cosmetic plastic surgery to refine and personalize the cosmetic treatment of factors affecting the appearance of the patient, which has achieved a good effect of structural integrity, functional perfection and beautiful appearance, which is widely recognized and praised by patients and their families.