The 5-year survival rate of sigmoid colon cancer a lymph node metastasis is usually around 50% for stage III and around 10% if it is stage IV. The occurrence of lymph node metastasis in sigmoid colon cancer indicates that the disease has developed to stage III, or even above stage III to stage IV. In this case, the possibility of complete eradication is very small, and only medical means can be used to inhibit the metastasis of cancer cells and thus achieve the purpose of delaying the disease. Generally speaking, if there is only regional lymph node metastasis, it should belong to stage III, and as long as it is actively treated, the 5-year survival rate can usually reach about 50%; if there is distant lymph node metastasis, it should belong to stage IV, and the 5-year survival rate can usually reach about 10%. Sigmoid colon cancer is mainly treated by surgery. Depending on the condition, healthcare professionals will use total or partial sigmoidectomy to relieve the condition. Chemotherapy regimens such as FOLFOX, XELOX, and others may also be used to kill cancer cells and inhibit cancer progression. Sigmoid colon cancer is more threatening to patients’ lives, so when the disease is found, it should be actively treated under the guidance of healthcare professionals, so as not to delay the disease and affect the quality of life.