Patients with tuberculosis tend to have low-grade fever, usually in the afternoon, night sweats, weakness, poor appetite, lethargy, and women may experience menstrual disorders. The general respiratory symptoms include coughing, hemoptysis, coughing sputum, chest pain, chest tightness of varying degrees, or difficulty in breathing. Generally when combined with tuberculous pleurisy, there will be a ferocious rubbing sound in the early stage, and when a large amount of pleural fluid is formed, chest tightness and shortness of breath will occur. Generally the chest wall will be full, the percussion will be turbid, and the fibrillation or breath sounds will be diminished or absent. Diagnosis generally requires a chest x-ray or CT, which is a necessary tool to determine the location and extent of tuberculosis and the progression of the lesion. Sputum smear, Mycobacterium tuberculosis, and tuberculin test are usually required.