Infant papular urticaria can be treated with oral medications and topical medications. 1. Oral medication: If the number of rashes in infants and young children is relatively large, if necessary, under the guidance of the doctor after weighing the pros and cons of the option of taking cetirizine drops for relief and improvement. 2. Topical medication: Infants with a small number of rashes and mild itching symptoms can be treated with topical zinc oxide boric acid ointment or vitamin E ointment, and if the skin breaks down due to scratching, mupirocin ointment can be used for anti-inflammatory treatment. Since the tolerance of infants is relatively poor, so in the drug treatment should follow the doctor’s instructions, to avoid blind use of drugs, causing discomfort and serious effects.