Clothes hurt when they rub against the skin may be due to herpes zoster, dengue, soft tissue contusion and other causes. 1. Herpes zoster: mainly in the body of varicella zoster virus after reactivation of the skin damage caused by the onset of the patient can appear along the nerve distribution of erythema, cluster blisters, accompanied by the Bureau of severe pain, which can cause clothing a rubbing skin pain. 2. Dengue: the disease is skin and subcutaneous tissue infected with type B hemolytic streptococcus and other acute inflammatory diseases. The affected area usually appears edematous erythema, with local burning, pain, which can appear as soon as the clothes rub the skin pain phenomenon. 3. Soft tissue contusion: may be due to collision, fall, hit and other violent reasons, caused by the patient’s local skin injury, so that the local pain, so that the clothes on the skin pain. Clothes rubbing skin pain may also be caused by other reasons, it is recommended that patients go to the regular hospital in a timely manner, in accordance with the doctor’s instructions for treatment, to avoid delaying the condition.