Individuals who get a tetanus shot will have a fever. A tetanus shot is a tetanus antitoxin that is given to prevent infection by the tetanus bacillus. Tetanus bacilli can generally be found on rusty nails, rusty knives, and other objects that can scratch. It is important to get a tetanus shot as soon as possible after being scratched by an object, especially a rusty one. The main tetanus shot side effects include anaphylaxis and serum sickness. Anaphylaxis can cause panic, shortness of breath, chest constriction, pallor, cold sweats, and chills in the extremities; serum sickness can cause swollen lymph nodes, hives, and fever, so individuals with tetanus injections can develop a fever. To summarize, before injecting tetanus antitoxin, you need to do a skin test, and if the skin test is negative, then you can inject it, which can prevent anaphylactic shock. After the injection of tetanus antitoxin, you need to observe whether there are any adverse reactions, if there are adverse reactions, you should go to the local hospital for treatment in time.