Vomiting blood in the advanced stage of lung adenocarcinoma should be stopped in time, and attention should be paid to clean up the bleeding in time to avoid suffocation, and blood transfusion can be made if necessary. Vomiting blood in advanced stage of lung adenocarcinoma is a more serious complication, which often endangers patients’ life because of asphyxiation, so hemostatic drugs should be given in time, and hemostasis can be performed under intervention if necessary. Lung adenocarcinoma with large tumor load in advanced stage is difficult to be cured clinically, so the final treatment effect is often unsatisfactory. In recent years, with the use of targeted and immune therapy, some patients can get longer survival time. Therefore, patients with advanced hemorrhage who can control the hemorrhage and stabilize it, and then choose the appropriate treatment, are likely to get better results.