Mesalazine treatment of ulcerative colitis, Crohn’s disease and other inflammatory bowel disease acute exacerbation, usually need to take the drug 8 to 12 weeks, but if serious adverse reactions need to stop. Mesalazine is mainly used for the treatment of ulcerative colitis, Crohn’s disease and other diseases, the specific course of treatment, need to be clinicians according to the condition of the comprehensive judgment; acute exacerbation of inflammatory bowel disease usually need to continue, regular use of medication for 8 to 12 weeks. However, it should be noted that the drug is contraindicated for allergy to drug components, renal or hepatic insufficiency, bleeding peptic ulcers or risk of bleeding, abnormal coagulation function, children and so on. Pregnant and breastfeeding women need to use it with caution after a thorough assessment of risks and efficacy. Adverse reactions such as severe convulsions, abdominal pain, fever, headache, rash, etc. need to stop the drug. The drug should be taken under the supervision of a physician.