Amoxicillin can be taken for lymph node inflammation because the most common clinical sites for lymph node inflammation are the neck and the inguinal region. The most common causes of lymphadenitis in the neck are oral cavity, gingivitis or upper respiratory tract infection, while lymphadenitis in the inguinal region is most commonly seen as a secondary result of lymphangitis of the lower extremities. This is because the most common causative organism in both lower extremity lymphangitis and oral pharyngitis is usually Staphylococcus aureus. At present, for Staphylococcus aureus, the main clinical application is a generation of cephalosporin or penicillin drugs, which can have a strong killing effect on it. Amoxicillin is a penicillin-like drug, so most lymphadenitis can be taken with amoxicillin and can get relief or even make the symptoms disappear.