The oral antihypertensive drugs for people with hypertension have no special effect on liver and kidney function. As long as the liver and kidney function of patients is normal, there is no need to pay special attention to the liver and kidney function damage of certain antihypertensive drugs. Mainstream antihypertensive drugs, such as calcium channel antagonists, such as nifedipine, ARB drugs, such as valsartan, ACEI drugs, such as captopril and diuretics, can be taken by people with normal liver and kidney function. If patients have severe liver function damage, drugs like nifedipine try to adjust the dose or change the medication, and those with severe kidney function damage can not choose drugs like valsartan, captopril or diuretics. But antihypertensive drugs have very little damage to the human liver and kidney function, and patients do not need to pay special attention.