A hard bump next to the nose may be due to an inflammatory reaction caused by acne. If it is an inflammatory reaction caused by acne, try to use mupirocin cream and fusidic acid cream for topical application first, and you can take oral antibiotics at the same time. In the early stage, you can take oral clindamycin and roxithromycin, or you can take oral doxycycline and memantine, but you cannot take them all orally, you can usually choose one. After the hard pack has subsided to a certain extent, you can take Tanshinone capsules orally, 3 times a day, 4 capsules a time, and pay attention to local skin cleanliness and try not to squeeze with your hands.