Abdominal cramps with severe pain can be seen in gastritis, enteritis, cholecystitis and other diseases, according to the type of disease through omeprazole, amoxicillin, ursodeoxycholic acid and other drugs conservative or surgical treatments to relieve the condition. 1. Gastritis: If the patient is accompanied by heartburn, acid reflux, vomiting, loss of appetite and other manifestations during the onset of the disease, it is mostly considered to be related to gastritis. For gastritis, it is recommended to take acid inhibitors such as omeprazole, gastric mucosa repair agents such as bismuth pectin, antibiotics such as clarithromycin capsules and amoxicillin for treatment. 2. Enteritis: patients with abdominal pain such as the lower abdomen or umbilical cord, accompanied by significant diarrhea, anxious and heavy (lower abdomen is uncomfortable, want to relieve stool, after defecation, there is a sense of defecation) and other manifestations, most of the consideration belongs to the symptoms of enteritis. It is recommended to take ciprofloxacin tablets and other antibiotics, with scopolamine tablets and other antispasmodic and analgesic drugs, with montelukast and other antidiarrheal drugs for treatment if necessary. 3. Cholecystitis: mostly pain in the right upper abdomen, accompanied by fever, vomiting, jaundice and other manifestations. Treatment can use cefotaxime sodium and other antibiotics, with scopolamine injection and other antispasmodic pain medication, as well as ursodeoxycholic acid and other choleretic drugs for conservative treatment. For severe conditions such as purulent cholecystitis or combined with peritonitis, doctors will recommend treatment through surgical methods such as cholecystectomy or cholecystostomy. Abdominal cramps accompanied by severe pain may also be due to a variety of other diseases, and should be promptly consulted for examination and treatment under the guidance of a doctor.