Joint wear includes wear of articular cartilage and wear of joint bone. Since articular cartilage is not renewable, it does not have independent blood circulation, and its nutrient supply and excretion of metabolites rely on joint fluid to complete, so if there is articular cartilage wear, for superficial damage, the wear can be repaired by swimming from deep cartilage to the surface. If the damage to the articular cartilage is heavy and the depth reaches the full layer, this repair is irreversible and the cartilage repair can be promoted by providing drugs and nutritional factors through the joint fluid. For joint bone damage and wear, as long as there is no obvious degeneration, hyperplasia or arthritis, the bone can be repaired by itself to achieve recovery. Therefore, the wear and tear of joints depends on whether it is the wear and tear of joint cartilage or the wear and tear of joint bones, and treatment should be carried out according to the different conditions.