Cranial repair is an ancient procedure, having been practiced by our ancestors thousands of years ago. After thousands of years of long development, it is now a very routine procedure in neurosurgery with very mature techniques, while cranial repair materials have been changed several times and have now reached a considerable height. Therefore, patients with cranial defects should put down their burdens and baggage and go for cranial repair surgery in time to restore their normal bodies, reintegrate into society and start a good life again. Some patients with cranial defects may ask whether it is better to use titanium alloy or simulation for cranial bone. It is true that titanium alloy has been widely used for a period of time, but there are some less than ideal conditions of titanium alloy, and many patients with cranial defects repaired by titanium alloy have had such and such problems, such as postoperative pain, sensitivity to heat and cold, postoperative infection, rejection reaction, postoperative interference with nuclear magnetic CT examination, etc. Therefore, titanium alloy is not the ideal choice of cranial bone repair material. As for the cranial bone with titanium alloy or simulated good, I think the “simulated” refers to the polyether ether ketone PEEK material, then of course is the simulation of good. This PEEK material is a bionic cranial bone, is a special polymer material, its performance is almost no different from the autologous cranial bone, polyetheretherketone PEEK has been widely used in clinical surgery, but also achieved very good clinical results, patients are very comfortable after surgery, very satisfied.