Itchy body once sleeping, consider hives, eczema, mite infection and other factors, need to go to the hospital in a timely manner to consult and identify, according to the different diseases for reasonable treatment. 1. Urticaria: Sleeping indoors at night is hot and stuffy or the blanket is thicker, which induces heat urticaria, leading to skin rash and itching. First of all, we need to remove the cause of the disease, to keep the indoor temperature cool; itching patients, you can take antihistamines, such as loratadine, etc.; can also be used to glycerine lotion topical application of urticaria, which can play the role of astringent and anti-itching. 2. Eczema: If the room is too humid and stuffy, it is easy to induce eczema when sleeping, and itching. Appropriate topical medications can be used to relieve itching and anti-inflammatory treatment, such as topical glucocorticoid hydrocortisone ointment, tretinoin cream, etc.; if the symptoms are more pronounced, oral antihistamines such as loratadine. 3. Mite infection: mites bite while sleeping, which can lead to mite dermatitis, resulting in local skin red papules, accompanied by itching symptoms. First of all, you need to disinfect and kill mites on bed sheets and bedding, and secondly, you can apply mite-killing and itch-relieving ointments such as sulfur ointment and glycerite lotion, which are commonly used. In addition, allergic dermatitis, geriatric pruritus, vegetative nerve dysfunction, etc., can be caused by itchy skin sleeping, it is recommended that the patient promptly to the hospital for diagnosis and identification, symptomatic treatment under the guidance of the doctor.