What is the role of tetanus

The tetanus vaccine is broadly useful for two purposes: 1. prevention; 2. treatment. Tetanus is a strictly anaerobic clostridium, after infection in the human body will release tetanus hemolytic toxin as well as spasm toxin, of which tetanus spasm toxin is the main pathogenic substance. The normal principle of prevention and treatment is to inject children at 3-6 months of age after birth to achieve basic immunity, and later injuries can be followed by a shot of chlorotoxin. If basic immunization is not performed, tetanus anticoagulant toxin TAT needs to be injected immediately after injury to obtain passive immunity. In addition, for those who have developed the disease, tetanus antitoxin should also be used in sufficient quantity in the early stage, because the generation of toxin binds to the cell receptor, the antitoxin will not be able to synthesize its toxic effect, so the mortality rate of tetanus is very high.