CD38 is a transmembrane glycoprotein on cells that plays an important role in promoting tumor growth and immune escape. CD stands for cluster of differentiation, which refers to molecules present on the surface of leukocytes, erythrocytes, platelets, and other tissue cells that can be recognized by antibodies, and CD molecules are often used as cellular markers for immune antigen recognition. Positive CD38 staining of the endometrium clinically suggests lymphocytic infiltration of the endometrium and can be used as a diagnostic pathology for endometritis. If you find positive CD38 staining, you need to ask a professional doctor to judge the test report in time. CD38 is a predictor of chronic B-lymphoblastic leukemia, and CD38 is highly expressed in many non-solid tumors (such as multiple myeloma) and solid tumors (such as breast cancer). Due to the high expression of CD38 in tumor cells, CD38 is currently used as a target for anticancer drugs, and two antibody drugs, daltuzumab and esatuximab, have been marketed.