Ovarian mass tumor markers usually refer to cancer antigen 125 (CA125), with a normal reference value of ≤35 U/ml, which is not serious. CA125 is a tumor-associated antigen, most commonly found in epithelial ovarian tumors (plasmacytoid tumors), its diagnostic specificity is poor, but the sensitivity is high. 80% of patients with epithelial tumors of the ovary CA125 is elevated, and 90% of patients with serum CA125 is related to the progression of the disease, CA125 elevation can also be seen in a variety of other diseases, such as ovarian cysts, uterine fibroid tumors, hepatitis, cirrhosis of the liver and so on. In short, ovarian mass tumor marker CA125 suggests normal without worry, but if elevated to more than twice the normal value, should be taken seriously, go to the hospital in time.