With the opening of China’s two-child policy, there are more and more older pregnant women. China stipulates that all pregnant women ≥35 years old are called older pregnant women, and older pregnant women should pay attention to the following matters: 1. increase the number of prenatal checkups, and perform timely ultrasound examination in early pregnancy to determine whether it is a normal pregnancy. Folic acid should be supplemented in time before and during the second trimester to prevent neurological malformations. 2. NT examination should be performed at 11-13 weeks plus 6 days. NT is an indicator reflecting early screening for trisomy 21, and if NT is thickened, prenatal diagnosis should be performed in time. For pregnant women over 35 years old, prenatal diagnosis is generally recommended, at least for non-invasive DNA test, amniocentesis and cord blood puncture; 3. Pay attention to diet adjustment, according to the body mass index, with professional nutritionist to give guidance. At the same time, moderate exercise, not to make itself and the fetus weight gain too fast; 4, older pregnant women, because the pelvis is more sclerotic, the elasticity of each joint ligament is not so good, the uterine contraction force is reduced, in labor is more likely to cause obstructed labor, postpartum bleeding, so after 36 weeks of pregnancy, according to their own situation, to decide the mode of delivery.