Prothrombin is the most important key step in the coagulation process that occurs in the body, and prothrombin is also known as coagulation factor II. In all coagulation processes, whether exogenous coagulation pathways or endogenous coagulation pathways, prothrombin is eventually activated to turn prothrombinogen into active thrombin. After activation of thrombin, fibrinogen can be activated to become active fibrin, and after activation of fibrin, fibrin multimers can be formed to accumulate at the broken blood vessels to achieve the purpose of hemostasis. And after activation of thrombin, it can rapidly improve the coagulation process, which is a positive feedback effect, leading to further acceleration of the human coagulation process. Therefore, thrombin plays a vital role in the human blood clotting process.