Hemoperfusion can remove medium and large molecules of toxins, while normal hemodialysis can only remove some small and medium molecules of toxins. Therefore, hemoperfusion is not only suitable for uremia, but also for some patients with drug or pesticide poisoning, liver failure or serious infection. The procedure of hemoperfusion: 1. For patients without vascular access, internal jugular vein placement or femoral vein placement should be performed to establish hemodialysis access. 2. Static heparinization of the perfusion device should be performed. 3. Pre-flush of the hemoperfusion device and line should be performed. If not only hemodialysis is done, but also general dialysis, pre-filling of the dialyzer and tubing should be done. 4. The hemodialysis machine should be put on the hemodialysis machine, and finally when the hemodialysis is finished, the hemodialysis machine should be removed, which is a complete hemodialysis operation process.