Rheumatology is an emerging clinical discipline. Its progress is closely related to the development of immunology, genetics, cell biology and other disciplines. Rheumatic diseases refer to a group of diseases affecting bones, joints and their surrounding soft tissues, muscles, bursae, tendons, fascia and the immune system. mucopolysaccharidosis, congenital chondrodysplasia, etc.), etc. Since many rheumatic diseases are chronic, recurrent, and even disabling, they are described abroad as the five “Ds”, i.e., death, disability, pain, economic loss, and drugtoxicity. Drugtoxicity, the harm of which can be imagined.