Scientifically, neonatal jaundice is not a contraindication to hepatitis B vaccination. The current hepatitis B vaccine is a genetically engineered vaccine, which is a surface antigen and not the virus itself. Therefore, jaundice does not affect the hepatitis B vaccination, and it will not aggravate jaundice or delay the time of jaundice subsiding after hepatitis B vaccination. If the jaundice is severe and the child’s general condition is poor, it is not recommended to get the hepatitis B vaccine, and the vaccine should be given after the jaundice subsides. This is because the child’s poor health condition will increase the risk of side effects from the vaccine. Nowadays, the vaccination requirements of the relevant immunization department are more stringent. In this case, it is recommended to communicate well that the risk of delaying the vaccination is greater than the risk of mild jaundice.