Proestrene Vaginal Gel Pills cannot usually be used directly without soaking. Prostacyclin vaginal gel pills on the vaginal mucosa can play the role of estrogen, can promote the proliferation of vaginal underlying cells, but also to maintain the normal acidic environment of the vagina, usually used for the treatment of estrogen deficiency caused by vaginal atrophic lesions, usually need to be wetted gel pills placed into the deep part of the vagina, is not recommended for direct use. Prostacyclin vaginal pills adverse reactions are not clear, estrogen-dependent cancer patients with a history of contraindication, patients with symptoms of discomfort can be timely to the hospital, under the guidance of the physician for related treatment, strict compliance with the doctor’s instructions to use the drug, to master the standardized way of using the drug, is conducive to the play of the efficacy of the drug.