L5-S1 herniated disc is a lumbar herniated disc, which can be treated with physical therapy, medication and surgery depending on the condition. 1. Physical therapy: If the condition is mild and only manifests symptoms such as low back pain, physical therapy such as extracorporeal shock wave, medium and low frequency electrotherapy, high energy laser therapy, heat therapy and massage can be given. 2. Medication: When the effect of physical therapy is not good, and the pain in the lower back is heavy, accompanied by mild nerve compression, painkillers such as ibuprofen, muscle relaxants such as tizanidine, dehydrating drugs such as mannitol, and nutritive nerve medications such as methylcobalamin can be given under the guidance of the doctor for treatment. 3. Surgery: If the condition is serious, conservative treatment is ineffective, combined with cauda equina nerve compression, limb paralysis, accompanied by muscle atrophy, muscle strength decline, etc., surgical treatment such as nucleus pulposus removal is needed. If L5-S1 herniated disc has been diagnosed, it is recommended to carry out standardized treatment as early as possible to reduce the adverse effects of the disease.