Heart failure three plus tricuspid valve severe regurgitation can be oral diuretic drugs to reduce the symptoms of heart acid, if necessary, surgical treatment to replace the valve. Heart failure three plus tricuspid valve severe regurgitation can be manifested as symptoms of heart failure, patients can appear dyspnea, gastrointestinal stasis, lower limb edema and other symptoms, oral furosemide, spironolactone and other drugs to diuretic and then reduce the heart load, accelerated heart rate of the patient can also be taken orally metoprolol treatment, accompanied by pulmonary artery severe hypertension patients, but also need to be given to the anisentan and other drugs to reduce the pressure of the pulmonary artery, the specific drugs should be developed in accordance with the patient’s condition. The specific medication should be formulated according to the patient’s condition. For patients with particularly severe valvular regurgitation, surgical treatment can be performed to replace the tricuspid valve, reduce the symptoms of massive tricuspid regurgitation, and effectively improve heart failure. Patients with heart failure grade III plus severe tricuspid regurgitation should choose the appropriate treatment plan under the guidance of a physician.