Breast squamous carcinoma has a high degree of malignancy, a short recurrence time, a high recurrence rate, and a lower overall survival rate than other types of invasive breast cancer. Breast squamous carcinoma is a special type of invasive breast cancer, which belongs to the metaplastic type of cancer and is usually considered to be originated from squamous metaplasia of ductal epithelial cells, and it is rare in clinic, accounting for less than 0.5% of breast cancers. Squamous carcinoma of breast is mainly manifested by solid lumps in the breast, which grows rapidly and can increase significantly within 2~3 weeks and even invade into the skin. The lymphatic metastasis rate of squamous breast cancer is higher than that of other invasive breast cancers, and those with rapid disease progression are also prone to hematogenous metastasis. Squamous breast cancer is highly malignant and its prognosis is even worse than that of triple-negative breast cancer. Patients with squamous breast cancer usually have early local recurrence, high recurrence rate and low overall survival rate. It is recommended that patients with squamous breast cancer should consult the doctor in time and take active treatment to avoid missing the best time for diagnosis and treatment.