Usually high low pressure is recommended to be treated with angiotensin receptor antagonists and beta blockers to lower blood pressure. High low pressure, generally refers to low pressure ≥ 90mmHg, high pressure < 140mmHg, the same can be diagnosed as hypertension. The cause of high low blood pressure is mainly related to the decrease of vascular elasticity, and the application of angiotensin receptor antagonist and β-blocker can be considered for antihypertensive treatment. 1. Angiotensin receptor antagonist. Commonly used, such as valsartan, chlorosartan, irbesartan, olmesartan, etc., can compete with angiotensin for receptors, thus making vasodilatation and lowering blood pressure, which can be used for the treatment of low-pressure people with high blood pressure, and at the same time there is also a certain degree of reduction in the filtration rate of the kidneys to achieve the control of proteinuria and other effects. 2. β-blocker: commonly used, such as metoprolol, bisoprolol, etc., the lowering effect is weaker, generally can be used for low blood pressure in the treatment of people with high blood pressure, but also can reduce the heart rate, used for panic attacks, coronary artery disease, palpitations, and hyperthyroidism patients treatment. Patients with high low blood pressure are advised to consult a doctor in time, follow the doctor's instructions for examination and treatment, and do not reduce or change the medication without authorization.