The causes of penile root ulceration and itching are infection, eczema, allergy, etc. Different drugs need to be selected according to different situations, including clotrimazole cream, halomethasone cream, and glycerite lotion. 1. Infection: local inflammation of hair follicles or when the local skin has damage to the bacterial and fungal infections, can cause penile root ulceration and itching, if the folliculitis or bacterial infections, can be treated with erythromycin ointment. If it is a fungal infection, you can use clotrimazole cream, terbinafine hydrochloride cream local application, pay attention to hygiene. Allergic to the drug is prohibited. 2. Eczema: when eczema occurs, you can use halometasone cream, dexamethasone cream, etc., ulcerated itchy parts can use boric acid solution wet compress. 3. Allergy: due to allergy to clothing, shower gel, etc., caused by itching, patients scratching excessively can also lead to the root of the penis ulcerated itching, you can use glycerine lotion to relieve, oral anti-allergy drugs such as loratadine, cetirizine. Allergic to drugs, severe renal impairment is prohibited. The root of the penis ulcerated itching caused by more diseases, should go to the hospital in a timely manner, diagnosed and treated by a professional doctor, follow the doctor’s instructions to use medication, not blindly self-medication.