High uric acid may be caused by diet, excessive production or decreased excretion of uric acid, and diseases. 1. Diet: when consuming too much high purine food, patients may have high uric acid, such as broth, animal offal, seafood, beer and so on. 2. Excessive generation or reduced excretion of uric acid: excessive generation of uric acid is generally caused by inborn purine metabolism disorders, generally associated with inactivation of the uric acid enzyme gene, related genetic defects in the transport process, uric acid synthesis and other factors. Uric acid is mainly excreted through the kidneys, such as kidney disease can cause uric acid excretion decrease. 3. Diseases: some blood diseases can lead to high uric acid due to excessive production of uric acid, such as leukemia, lymphoma, multiple myeloma, etc. It may also be caused by chronic kidney disease, the patient’s renal tubules will be due to the decrease in secretion of uric acid and the increase in uric acid. The specific causes of high uric acid need to go to the hospital for further examination to determine, after diagnosis under the guidance of the doctor for treatment.