Rabeprazole can be taken together with aluminum thioglycollate gel. Rabeprazole is a proton pump inhibitor, which can inhibit the secretion of gastric acid by gastric mucosal wall cells, and is mainly used in the treatment of gastric ulcer, duodenal ulcer, anastomotic ulcer, reflux esophagitis, Dreu-Ayres Syndrome (Gastrinoma) and other diseases in the clinic. However, Rabeprazole may cause constipation, diarrhea, abdominal distension, headache, rash and other adverse reactions when taking it, and should be used with caution for pregnant women, lactating women, children, the elderly, and patients with hepatic insufficiency. Aluminum thioglycollate gel is a sucrose sulfate complex containing aluminum hydroxide, which can be polymerized into a colloid under acidic conditions in the stomach to form a thin film directly on the ulcer surface or inflammation to protect the damaged gastric mucosa, and is mainly used in the clinical treatment of gastric ulcers, duodenal ulcers, acute and symptomatic chronic gastritis, gastritis caused by non-steroidal anti-inflammatory drugs, esophageal ulcers and other diseases. However, thioglycollate gel can be taken with constipation, dry mouth, diarrhea, rash, itching, facial edema, fatigue, dizziness, insomnia and liver transaminase elevation and other adverse reactions, for the first trimester of pregnancy, habitual constipation, hepatic and renal insufficiency should be used with caution. Rabeprazole and aluminum thioglycollate gel taken together can reduce gastric acid secretion, protect the gastric mucosa, gastric, duodenal ulcer, reflux esophagitis and other diseases have a better therapeutic effect, usually can be taken together. However, due to the differences in personal constitution and condition, rabeprazole and aluminum thioglycollate gel should be taken in advance to consult the doctor, strictly according to the doctor’s instructions, not self-medication, so as not to delay or even aggravate the condition.