Sudden attack of gout may be related to not regular use of uric acid-lowering drugs, not regular low purine diet, strenuous exercise and other reasons, and can be treated with medication and non-pharmacological treatment. 1. Drug therapy: acute gout attack should be used as soon as possible to control symptoms, such as indomethacin and other non-steroidal anti-inflammatory drugs, colchicine, such as dexamethasone and other glucocorticosteroids can significantly relieve the symptoms of joint swelling and pain. However, in the acute exacerbation period generally do not add the use of allopurinol and other uric acid-lowering drugs, to avoid the fluctuation of blood uric acid aggravate the condition. The above drugs should be used according to the doctor’s instructions. 2. Non-pharmacological treatment: avoid drinking alcohol and fructose-rich beverages, avoid eating high purine foods such as liver, and pay attention to weight control, regular exercise, drink more water, etc. During gout attacks and the inter-episode period, we recommend that you go to a regular medical center in time. When gout attack, it is recommended to go to the rheumatology and immunology department of the regular hospital in time, follow the doctor’s instructions to take medication to relieve the symptoms, and pay attention to improve the related lifestyle habits.