Hand, foot and mouth disease in children is an acute febrile rash caused by enterovirus infection, and the danger is mainly manifested in the following aspects: First, there is damage to the skin mucosa of the mouth, hands, feet and buttocks, causing physical discomfort. Second, different degrees of fever can consume energy and cause a decrease in quality of life. Third, HFMD is an intestinal virus, which can affect the digestive system and cause nausea, vomiting, abdominal pain and other symptoms of digestive discomfort. Fourth, some children with severe HFMD may also affect the heart and lung function, affecting the nervous system leading to respiratory failure, heart failure, brain stem encephalitis and other serious diseases, which may leave sequelae.