Azithromycin is a macrolide antibiotic, clinically for gram-negative cocci, positive cocci and negative bacilli have a strong antibacterial effect, otitis media is mainly bacterial infection caused by purulent otitis media inflammatory infection. Clinically, it is mainly streptococcus, staphylococcus, so azithromycin has a very good therapeutic effect on otitis media, azithromycin can be taken for 3-5 days of treatment, can be divided into oral or once oral. Azithromycin for otitis media should be noted that there is a certain gastrointestinal reaction, so it is best to use after meals.