Multiple lumps in the clavicle fossa are painless and itchy, which may be suffering from lipoma, multiple lipocystic tumors, enlarged lymph nodes and other conditions. 1. Lipoma: it is a fatty mass protruding from the skin due to the accumulation of fat cells between the skin and muscle during the growth of fat cells, it is more common in the limbs and trunk, it is soft in texture, and it can be slightly moved when pressed, and there is no pain in general without compression of the nerves. 2. Multiple lipodystrophy: it belongs to autosomal dominant genetic disease, related to congenital chancroid, ectodermal dysplasia, etc. It also leads to multiple lumps in the clavicular fossa without pain or itching. 3. Enlarged lymph nodes: if the organism is stimulated or damaged, as well as suffering from tumors, local infections and other factors may lead to enlarged lymph nodes, which need to be clearly identified after the cause of the disease, using antibiotics, glucocorticoids and other drugs or surgical treatment. Clavicular fossa has more than one lump painless and itchy, may also be other diseases, it is recommended to go to the regular hospital in the physician examination and then symptomatic treatment, avoid self-medication, in order to avoid other adverse reactions.