The risk of ventricular premature contractions varies depending on the location and frequency of their origin and may be life-threatening in severe cases. The risk of premature ventricular contractions depends on the site of origin and frequency of the contractions and the underlying condition of the patient’s heart. In healthy people, occasional premature ventricular contractions that do not cause other types of arrhythmias at the site of origin do not have a significant impact on health and should not be overly alarming. Ventricular premature beats that may induce other ventricular arrhythmias, such as ventricular tachycardia and ventricular fibrillation, have a risk of sudden cardiac death and should be treated promptly with medication or radiofrequency ablation, regardless of the frequency of premature beats, to avoid life-threatening situations. Frequent premature ventricular contractions can lead to distant structural and morphological changes in the heart, which may cause heart failure and other diseases, and should also be treated early. In patients with underlying heart disease, premature ventricular contractions may aggravate the degree of the primary disease and cause deterioration of cardiac function, etc., and require adjustment of medication based on the treatment of the primary disease under the guidance of a specialist physician. Premature ventricular contractions that can trigger other types of ventricular arrhythmias at the site of origin may be life-threatening. Prolonged and frequent premature ventricular contractions can cause structural and functional changes in the heart. Therefore, it is important to consult a regular hospital as soon as possible once detected.