Premature ventricular contractions (ventricular premature) are the most common type of clinical arrhythmia. Ventricular premature beats are commonly seen in patients with coronary artery disease, cardiomyopathy and mitral valve prolapse, but can also be seen in people with normal heart structure, known as idiopathic ventricular premature beats. The symptoms of ventricular premature beats are highly variable, ranging from complete asymptomatism with mild palpitations and breath-holding discomfort to syncope and even sudden death due to malignant ventricular arrhythmias triggered by premature beats. Patients with episodic ventricular premature beats are usually asymptomatic or have occasional palpitations, chest tightness, and other discomfort. Patients with frequent ventricular premature beats often have palpitations and even angina symptoms. Patients feel symptoms such as suffocation and crushing pain in the precordial region during ventricular premature attacks. The most common symptom of ventricular premature is palpitations, which arise mainly due to the enhanced heartbeat after premature beats and compensatory intervals (i.e., long intervals between heartbeats after ventricular premature). When ventricular premature episodes are frequent or in duplex rhythm it can lead to a significant decrease in cardiac output, and patients may experience dizziness and other symptoms. Prolonged and frequent attacks of ventricular premature can cause a decline in cardiac function and, in severe cases, heart failure. Severe organic heart disease such as coronary artery disease, acute myocardial infarction, cardiomyopathy, and heart failure can also trigger frequent ventricular premature beats, which should be treated actively and, if necessary, hospitalized. A few premature ventricular beats may occur in normal people when they are emotionally agitated, stressed or overworked, and usually do not exceed 100 beats/24 hours. For occasional premature ventricular contractions without organic heart disease, we do not need to apply anti-arrhythmic drugs. With proper rest, elimination of mental tension and change of bad habits, premature ventricular contractions can disappear. What deserves our attention are those ventricular premature beats caused by organic heart disease, such as coronary heart disease, cardiomyopathy, heart failure, or serious electrolyte and acid-base balance disorders, such as severe hypokalemia and hypomagnesemia. The danger of such premature ventricular contractions is that they may trigger ventricular tachycardia and lead to increased mortality. Therefore, these patients with frequent ventricular premature events need to be treated by actively searching for the cause of the ventricular premature events. In addition to coronary heart disease, acute myocardial infarction, heart failure, various other heart diseases such as hypertensive heart disease, cardiomyopathy, heart valve disease, and even hyperthyroidism can trigger ventricular premature. Of course, sometimes some of the drugs used to treat arrhythmias themselves, as well as some antidepressants, can also trigger ventricular premature. In addition, ventricular prematureness can also occur frequently when the body is in a state of low blood potassium, low blood magnesium, low blood calcium, hypoxia, acidosis, etc. If the cause of ventricular premature is treated, it can often achieve very good results. If ventricular premature still occurs frequently after correcting the cause or controlling the primary disease, it needs to be treated with antiarrhythmic drugs. The treatment effect is often very good. Therefore, patients with organic heart disease such as coronary artery disease or heart failure should pay special attention to frequent premature ventricular contractions and seek prompt medical attention. The traditional view is that ventricular premature contractions with no known cause do not need to be treated if there are no symptoms. However, recent studies suggest that prolonged and frequent ventricular premature contractions can cause tachycardia and cardiomyopathy and lead to heart failure even if there are no symptoms. Therefore, it is important to control the frequency of ventricular premature episodes or even eradicate them completely to avoid the development of cardiomyopathy. Therefore, for these patients with frequent ventricular premature episodes without organic heart disease, drugs such as β-blockers or other antiarrhythmic drugs should be selected for treatment, and if drug control is poor, radiofrequency ablation should be selected for treatment, with an efficiency of more than 90%. In conclusion, for frequent ventricular premature beats, we should not be paralyzed, we should actively search for the cause of ventricular premature and correct it in time, and for those who are not well controlled by drugs, we should actively choose radiofrequency ablation therapy at an early stage, and we should not miss the good opportunity of treatment, the overall treatment goal of radiofrequent ventricular premature beats ablation therapy is to completely eradicate the ventricular premature trigger lesion and avoid the deterioration of heart function.