The difference between influenza and the common cold lies mainly in the causative pathogen, clinical manifestations, and severity. 1. Causative agent: Common cold is usually caused by adenovirus, rhinovirus, respiratory syncytial virus and other infections; influenza is mainly caused by influenza virus infection. 2. Clinical manifestations: the common cold is mainly characterized by upper respiratory tract symptoms, including sneezing, nasal congestion, watery nasal discharge, etc., and some of them may also have cough and dry throat. Influenza is characterized by milder symptoms and more severe systemic symptoms, usually with an acute onset, high fever, headache, fatigue, and generalized muscular symptoms. 3. Severity: Influenza is usually more serious than the common cold, and can cause outbreaks of epidemics, and can be combined with severe pneumonia. If you feel unwell, it is recommended to consult a doctor in time.