To change from lamotrigine to valproate you need to add valproate first, then taper off the moratrigine after the seizures are controlled or the maximum tolerable dose is reached, and keep taking valproate alone thereafter. The medication must be administered under the supervision of a physician. It is appropriate to increase the medication faster in epilepsy, but the reduction must be slow and care should be taken during the change of medication. The addition of sodium valproate can be increased to a therapeutic dose for a short period of time, and then the two drugs are taken at the same time for 5-7 days, then slowly reduce the dosage of lamotrigine. The specific method of reducing lamotrigine can be done by reducing the dose by one-quarter every 2 to 4 weeks. If the seizures can be controlled by Lamotrigine, it is not recommended to switch to other drugs to avoid the emergence of status epilepticus. It is recommended that the patient go to the neurology clinic of the hospital to consult the doctor and adjust the treatment plan under the doctor’s advice.