Knee pain going up and down stairs should be treated according to the cause. Common causes include meniscus injury, ligament injury, patellar wear and tear, joint inflammation, etc. Treatment includes physical therapy, medication and surgery. 1. Meniscus injury: mostly caused by trauma, treatment includes conservative treatment and arthroscopic surgery. Incomplete tear can be treated conservatively; if the old injury reoccurs acutely after conservative treatment, it should be treated surgically, such as meniscus suture surgery, meniscectomy. 2. Ligament injury: Knee sprains can cause tears of the medial and lateral knee ligaments. It can be treated by rest, cold compresses within 72 hours, hot compresses after 72 hours, and acupuncture and massage. Physical therapy such as direct current, light therapy, ultrasound, and magnetic therapy can also be used. 3. Patellar wear: Long-term exertion of the knee will cause wear and tear of the patella. Painful symptoms should limit the activities of the knee joint, when the swelling and pain is obvious, first cold compresses and then hot compresses, with physical therapy or intra-articular injection of sodium vitrate, conservative treatment is ineffective and feasible surgical treatment. 4. Joint inflammation: rheumatoid arthritis, rheumatoid arthritis, etc., the acute phase should rest, avoid cold, anti-rheumatic preferred non-steroidal anti-inflammatory drugs, such as celecoxib, glucocorticosteroids such as prednisone, dexamethasone can also be used. If necessary, ibuprofen and panax ginseng tablets can be used to activate blood circulation, reduce swelling and relieve pain. If you have knee pain or the symptoms are not relieved, you should go to the hospital to see a doctor to find out the cause of the pain and then give targeted treatment. The above drugs should be used under the guidance of a doctor, avoid self-medication.