Taking rivaroxaban and then taking Gui Long ointment generally has no special side effects, you should consult a Western physician or Chinese medicine practitioner for evidence-based guidance and follow the doctor’s instructions for medication. Rivaroxaban mainly through the inhibitor of factor Xa to achieve the effect of coagulation, as long as used for hypercoagulation, atrial fibrillation, thrombosis and other patients, side effects may appear skin mucous membrane bleeding, gastrointestinal bleeding, cerebral hemorrhage, and other bleeding; pregnancy, lactation, and children under the age of 18 years old has not yet been a clear safety data, it is not recommended to apply. Gui Long Ointment dispels wind and removes dampness, soothes tendons and activates collaterals, warms the kidney and replenishes blood. It is used for rheumatism and bone pain, chronic lumbar and leg pain, anemia caused by deficiency of kidney yang and qi and blood, insomnia, shortness of breath, palpitation (accelerated heartbeat, often accompanied by panic), excessive sweating, anorexia, abdominal distension, and frequent urination, and is forbidden to be applied to pregnant women and children. There are no significant side effects when both are used together, but specific medications should be used after consulting a physician.