The main differences between biologic and mechanical valves are different materials, different prices, and different durations of use. Biological valves are mainly made of biomaterials, such as porcine valves or bovine pericardium, and mechanical valves are made of non-biological materials, such as carbon or metal, both of which have the function of natural heart valves and can replace diseased valves. Biologic valves have poor durability, with a life expectancy of 10 to 20 years, and need to be replaced again after valve destruction; mechanical valves have good durability and can theoretically be used for life, but require lifelong use of anticoagulant medications, such as warfarin, after surgery. In terms of price, biologic valves are more expensive than mechanical valves because they are handmade, but in terms of overall outcomes for patients of all ages, there is not much difference in the long-term survival rates of the two types of valves. If valve replacement surgery is needed, it is recommended to follow your doctor’s instructions.