For patients with hypertension whose blood pressure does not drop after taking antihypertensive drugs, adjustments can be made in the following ways: 1. The dose of the drug can be increased, and if the blood pressure does not drop significantly after taking one antihypertensive drug, the amount of the drug can be increased on top of the original one, for example, the drug can be taken in the morning and in the afternoon. 2. If the medication does not fall, you can increase the application of diuretics or beta-blockers and other drugs to take a combined antihypertensive approach to reduce blood pressure. 3, you can also make self-adjustment through some lifestyle changes, such as quitting smoking and drinking, early to bed and early to rise, to avoid excessive anxiety, sympathetic excitement and other factors, can play a role in regulating blood pressure effect.