Mucus with blood in stool may be due to colorectal cancer, bacillary dysentery, ulcerative colitis, etc. You may cooperate with doctor to receive surgery, medication and other treatments to improve the symptoms. 1. Colorectal cancer: When malignant cells invade blood vessels in colorectal cancer, it may cause blood vessels to rupture and bleed, which may lead to blood in stool mucus. Surgery to remove diseased tissues and clear nearby lymph nodes should be considered for treatment, combined with radiotherapy and chemotherapy (e.g. 5-FU, mitomycin, etc.) for comprehensive treatment after surgery. 2. Bacterial dysentery: Bacterial dysentery can lead to inflammatory reaction of the intestinal mucosa, which can also lead to mucus with blood in the stool. Antibiotics such as quinolone and azithromycin should be used as prescribed to help improve the condition. 3. Ulcerative colitis: the mucous membrane of the intestine of patients with ulcerative colitis is in a state of congestion and edema, which can easily lead to mucus with blood in the stool. Aminosalicylic acid, mesalazine, prednisone and other drugs can be used to help improve the symptoms. If there is blood in the stool mucus for a long time, it may also be caused by other diseases such as colon polyps. It is recommended that you go to the hospital to get a clear picture of the cause of the disease and receive treatment.