Depression with western medicine and Chinese medicine treatment have some effect, usually western medicine as the main, Chinese medicine as a supplement, it is recommended to cooperate with the doctor’s analysis and guidance to choose. 1. Western medical treatment: For moderate and severe depression, it is usually recommended to use western medicine for treatment. After stabilizing the condition with western medicine, Chinese medicine can be used for maintenance and consolidation. Commonly used drugs include sertraline hydrochloride tablets, duloxetine, venlafaxine and so on, which can improve the patient’s depressive state. If the effect is not good, then use the second line of antidepressants, such as chlorpromazine, amitriptyline, doxepin and so on. 2. Traditional Chinese medicine treatment: For mild and moderate depression, traditional Chinese medicine can be chosen for treatment, such as Ba Ji Tian Oligosaccharide Capsule, Xie Yu An Shen Granules, Shu Hepatolytic Capsule, etc. These medicines have the effect of strengthening the spleen and tranquillizing the mind (strengthening the function of the spleen and stabilizing the mind), dredging the liver and relieving depression (treating depression by dredging the liver qi), which can help to alleviate the symptoms of depression. According to the actual situation of the patient’s condition, treatment can be carried out under the guidance of the doctor, do not blindly use medication on your own, so as not to cause delays in the condition.