High glycoantigen 199U/ml can be seen in three situations: the first situation, seen in normal people, such as smoking, drinking and staying up late can lead to a transient increase in glycoantigen 199; the second situation, seen in some non-malignant lesions, such as diabetic patients, inflammation or stones of the gallbladder, renal insufficiency, acute and chronic pancreatitis and liver cirrhosis, in these benign lesions, glycoantigen 199U/ml is often transiently elevated and the concentration is not too high; the third situation, seen in some malignant lesions, mainly tumors of the gastrointestinal tract, such as gallbladder cancer, liver cancer, pancreatic cancer and nodules. 199U/ml is often elevated transiently and the concentration is mostly not too high; in the third case, it can be seen in some malignant lesions, mainly tumors of the gastrointestinal tract, such as gallbladder cancer, liver cancer, pancreatic cancer, colon cancer and gastric cancer, which can be primary tumors or metastatic tumors of the digestive tract. If these tumors are treated with radiotherapy and the disease is controlled, the concentration of glycogen 199U/ml will also decrease significantly, so it is often used as an indicator to observe the effect of treatment.