Pediatric fever of 39 degrees or more there is no fixed rapid cooling method, need to use antipyretic drugs to lower the temperature at the same time to clarify the cause of the fever to take targeted measures, otherwise the fever will recur. Children with a fever of 39 degrees or more first need to use antipyretic drugs and with physical cooling, such as ibuprofen, acetaminophen, etc., physical cooling can be taken to the head of the antipyretic patch or warm water bath. Secondly, we should actively go to the hospital for blood tests, such as bacterial infections need to use cefixime, amoxicillin and other antibiotic treatment. Pediatric fever of 39 degrees if the fever has been high, it is recommended to go to the hospital in a timely manner for relevant examinations to clarify the specific causes, and actively cooperate with the doctor’s treatment, so as to avoid delaying the condition, the above drugs need to be used under the guidance of the doctor, avoid self-medication.